Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.

This research investigated the profile of anti-Leishmania antibodies in different clinical forms of canine visceral leishmaniasis (CVL). Naturally infected dogs were divided into two groups: subclinical dogs (SD, n = 10) and clinical dogs (CD, n = 68). Non-infected dogs (ND, n = 7) comprised the neg...

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Autores: Freitas, José Cláudio Carneiro de, Lopes Neto, Belarmino Eugênio, Abreu, Cyntia Rafaelle Amaral de, Vital, Wendel Coura, Braga, Samuel Leôncio, Reis, Alexandre Barbosa, Pinheiro, Diana Célia Sousa Nunes
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Brasil
Institución:Universidade Federal de Ouro Preto (UFOP)
Repositorio:Repositório Institucional da UFOP
Idioma:inglés
OAI Identifier:oai:repositorio.ufop.br:123456789/4259
Acceso en línea:http://www.repositorio.ufop.br/handle/123456789/4259
https://doi.org/10.1016/j.rvsc.2011.12.009
Access Level:acceso abierto
Palabra clave:Leishmania antibodies
Canine visceral leishmaniasis
Clinical pictures
Leishmania chagasi
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spelling Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.Leishmania antibodiesCanine visceral leishmaniasisClinical picturesLeishmania chagasiThis research investigated the profile of anti-Leishmania antibodies in different clinical forms of canine visceral leishmaniasis (CVL). Naturally infected dogs were divided into two groups: subclinical dogs (SD, n = 10) and clinical dogs (CD, n = 68). Non-infected dogs (ND, n = 7) comprised the negative control group. The humoral response was evaluated by the profile of total IgG, IgG1, IgG2, IgM, IgA and IgE, determined by ELISA. Infected animals showed increased levels of total IgG, IgA and IgE in addition to IgG1 and IgG2 in groups SD and CD, when compared with group ND. Furthermore, it was observed that IgG2 and IgM were correlated with symptomatology, while total IgG, IgG1 and IgA were negatively correlated and IgE showed no correlation. It follows that serum levels of IgG2 anti-Leishmania are correlated with typical clinical signs of disease. Furthermore the determination of specific anti-Leishmania antibodies could be an important tool in monitoring CVL clinical picture.2015-01-19T16:34:58Z2015-01-19T16:34:58Z2012info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfFREITAS, J.C. C. de et al. Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis. Research in Veterinary Science, v. 93, p. 705-709, 2012. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0034528811004711>. Acesso em: 13 ago. 2014.0034-5288http://www.repositorio.ufop.br/handle/123456789/4259https://doi.org/10.1016/j.rvsc.2011.12.009ark:/61566/001300000hbj2O periódico Research in Veterinary Science concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3442010848687.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPFreitas, José Cláudio Carneiro deLopes Neto, Belarmino EugênioAbreu, Cyntia Rafaelle Amaral deVital, Wendel CouraBraga, Samuel LeôncioReis, Alexandre BarbosaPinheiro, Diana Célia Sousa Nunes2024-11-11T06:25:36Zoai:repositorio.ufop.br:123456789/4259Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332024-11-11T06:25:36Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false
dc.title.none.fl_str_mv Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
title Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
spellingShingle Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
Freitas, José Cláudio Carneiro de
Leishmania antibodies
Canine visceral leishmaniasis
Clinical pictures
Leishmania chagasi
title_short Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
title_full Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
title_fullStr Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
title_full_unstemmed Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
title_sort Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis.
dc.creator.none.fl_str_mv Freitas, José Cláudio Carneiro de
Lopes Neto, Belarmino Eugênio
Abreu, Cyntia Rafaelle Amaral de
Vital, Wendel Coura
Braga, Samuel Leôncio
Reis, Alexandre Barbosa
Pinheiro, Diana Célia Sousa Nunes
author Freitas, José Cláudio Carneiro de
author_facet Freitas, José Cláudio Carneiro de
Lopes Neto, Belarmino Eugênio
Abreu, Cyntia Rafaelle Amaral de
Vital, Wendel Coura
Braga, Samuel Leôncio
Reis, Alexandre Barbosa
Pinheiro, Diana Célia Sousa Nunes
author_role author
author2 Lopes Neto, Belarmino Eugênio
Abreu, Cyntia Rafaelle Amaral de
Vital, Wendel Coura
Braga, Samuel Leôncio
Reis, Alexandre Barbosa
Pinheiro, Diana Célia Sousa Nunes
author2_role author
author
author
author
author
author
dc.subject.por.fl_str_mv Leishmania antibodies
Canine visceral leishmaniasis
Clinical pictures
Leishmania chagasi
topic Leishmania antibodies
Canine visceral leishmaniasis
Clinical pictures
Leishmania chagasi
description This research investigated the profile of anti-Leishmania antibodies in different clinical forms of canine visceral leishmaniasis (CVL). Naturally infected dogs were divided into two groups: subclinical dogs (SD, n = 10) and clinical dogs (CD, n = 68). Non-infected dogs (ND, n = 7) comprised the negative control group. The humoral response was evaluated by the profile of total IgG, IgG1, IgG2, IgM, IgA and IgE, determined by ELISA. Infected animals showed increased levels of total IgG, IgA and IgE in addition to IgG1 and IgG2 in groups SD and CD, when compared with group ND. Furthermore, it was observed that IgG2 and IgM were correlated with symptomatology, while total IgG, IgG1 and IgA were negatively correlated and IgE showed no correlation. It follows that serum levels of IgG2 anti-Leishmania are correlated with typical clinical signs of disease. Furthermore the determination of specific anti-Leishmania antibodies could be an important tool in monitoring CVL clinical picture.
publishDate 2012
dc.date.none.fl_str_mv 2012
2015-01-19T16:34:58Z
2015-01-19T16:34:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv FREITAS, J.C. C. de et al. Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis. Research in Veterinary Science, v. 93, p. 705-709, 2012. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0034528811004711>. Acesso em: 13 ago. 2014.
0034-5288
http://www.repositorio.ufop.br/handle/123456789/4259
https://doi.org/10.1016/j.rvsc.2011.12.009
dc.identifier.dark.fl_str_mv ark:/61566/001300000hbj2
identifier_str_mv FREITAS, J.C. C. de et al. Profile of anti-Leishmania antibodies related to clinical picture in canine visceral leishmaniasis. Research in Veterinary Science, v. 93, p. 705-709, 2012. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0034528811004711>. Acesso em: 13 ago. 2014.
0034-5288
ark:/61566/001300000hbj2
url http://www.repositorio.ufop.br/handle/123456789/4259
https://doi.org/10.1016/j.rvsc.2011.12.009
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFOP
instname:Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
instname_str Universidade Federal de Ouro Preto (UFOP)
instacron_str UFOP
institution UFOP
reponame_str Repositório Institucional da UFOP
collection Repositório Institucional da UFOP
repository.name.fl_str_mv Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)
repository.mail.fl_str_mv repositorio@ufop.edu.br
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score 15,300719

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