In situ effect of a proanthocyanidin mouthrinse on dentin subjected to erosion
Proanthocyanidin has been shown to be efficient in inhibiting matrix metalloproteinases. Objective: The aim of this in situ study was to evaluate the protective effect of Proanthocyanidin-based mouthrinses either with naturally acidic or with a neutral pH applied on dentin subjected to erosion. Meth...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Universidade de São Paulo (USP) |
| Repositorio: | Journal of applied oral science (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:revistas.usp.br:article/190672 |
| Acceso en línea: | https://www.revistas.usp.br/jaos/article/view/190672 |
| Access Level: | acceso abierto |
| Palabra clave: | Tooth wear Dentin Tooth erosion |
| Sumario: | Proanthocyanidin has been shown to be efficient in inhibiting matrix metalloproteinases. Objective: The aim of this in situ study was to evaluate the protective effect of Proanthocyanidin-based mouthrinses either with naturally acidic or with a neutral pH applied on dentin subjected to erosion. Methodology: Eight volunteers wore one palatal device in two phases (7 days washout) with 16 samples per group (n=8). The groups under study were: First Phase/ G1 – 10% proanthocyanidin mouthrinse (pH 7.0, Experimental group 1 – Purified Grape Seeds Oligomeric Proanthocyanidins), G2 – 10% proanthocyanidin mouthrinse (pH 3.0, Experimental group 2 – Purified Grape Seeds Oligomeric Proanthocyanidins). Second Phase/ G3 – 0.12% chlorhexidine mouthrinse (pH 7.0, Positive control group), G4 – no previous treatment (Negative control group). Each device was subjected to 3 erosive cycles (5 minutes) per day for 5 days. Treatments with different mouthrinses were applied once after the second erosive challenge (5 minutes). Profilometry was used to quantify dentin loss (µm). Results: Data were analyzed by repeated measures of ANOVA followed by Fisher’s test (p<0.05). G1 (1.17±0.69) and G3 (1.22±0.25) showed significantly lower wear values with no statistical difference between them. G2 (2.99±1.15) and G4 (2.29±1.13) presented higher wear values with no significant differences between them. Conclusion: The 10% proanthocyanidin mouthrinse (pH 7.0) could be a good strategy to reduce dentin wear progression. |
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