Adverse drug events in hospitalized patients in Brazil: Integrative literature review

Objective: Analyzing studies related to Adverse Drug Events (ADE) in hospitalized patients in Brazil. Method: integrative review, for which the National Library of Medicine (PubMed), Biblioteca Virtual de Saúde (BVS), Repository of the Fundação Oswaldo Cruz (FIOCRUZ) and Capes Journals databases wer...

Descripción completa

Detalles Bibliográficos
Autores: Sousa, Chriscia Jamilly Pinto, Prete, Ana Cristina Lo, Gomes, Amanda Gabriele Piedade, Castro, Eline Fernandes Ribeiro de, Ribeiro, Carolina Heitmann Mares Azevedo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Federal de Itajubá (UNIFEI)
Repositorio:Research, Society and Development
Idioma:inglés
OAI Identifier:oai:ojs.pkp.sfu.ca:article/13818
Acceso en línea:https://rsdjournal.org/index.php/rsd/article/view/13818
Access Level:acceso abierto
Palabra clave:Efeitos colaterais e reações adversas relacionados a medicamentos
Farmacovigilância
Indicadores de qualidade em assistência à saúde.
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos
Farmacovigilancia
Indicadores de Calidad de la Atención de Salud
Drug-related side effects and adverse reactions
Pharmacovigilance
Quality indicators, health care.
Descripción
Sumario:Objective: Analyzing studies related to Adverse Drug Events (ADE) in hospitalized patients in Brazil. Method: integrative review, for which the National Library of Medicine (PubMed), Biblioteca Virtual de Saúde (BVS), Repository of the Fundação Oswaldo Cruz (FIOCRUZ) and Capes Journals databases were selected for searching the studies primary, with the descriptors: Patient Safety, Drug-related side effects and adverse reactions, Patient harm, Hospitalization, Inpatients. Results: Twenty articles were identified, 50% (10) were from the southeast region of Brazil. Regarding the methodology adopted to identify the ADEs, 70% (14) used the retrospective data review. The trackers were used in 5 (25%) articles, 3 of which used the triggers proposed by the Institute for Healthcare Improvement, and the other 2 the trackers used were proposed by the researchers themselves. The number of adverse drug reactions ranged from 12 to 96, while the occurrence of AE ranged from 4 to 122. In one study 50% (41) of participants had at least one adverse drug event. Conclusion: There is great variability in scientific production in Brazil, and in the occurrence of Adverse Drug Events as well. There is a need for strategies to identify these events and create strategies to promote patient safety.