Multicatalytic hybrid materials for biocatalytic and chemoenzymatic cascades-strategies for multicatalyst (enzyme) co-immobilization
During recent decades, the use of enzymes or chemoenzymatic cascades for organic chemistry has gained much importance in fundamental and industrial research. Moreover, several enzymatic and chemoenzymatic reactions have also served in green and sustainable manufacturing processes especially in fine...
| Autores: | , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Universidade Federal de Minas Gerais (UFMG) |
| Repositorio: | Repositório Institucional da UFMG |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/55643 |
| Acceso en línea: | https://doi.org/10.3390/catal11080936 http://hdl.handle.net/1843/55643 https://orcid.org/0000-0002-3344-4084 https://orcid.org/0000-0002-5625-7337 https://orcid.org/0000-0002-6422-4025 https://orcid.org/0000-0002-8956-5846 https://orcid.org/0000-0003-0725-0881 https://orcid.org/0000-0002-8887-2772 |
| Access Level: | acceso abierto |
| Palabra clave: | Enzymes Immobilization Chemoenzymatic cascades Biocatalysis Nanomaterials Enzimas Síntese orgânica Materiais nanoestruturados Adsorção Biopolímeros Espectroscopia de ressonância nuclear Termodinamica Catálise |
| Sumario: | During recent decades, the use of enzymes or chemoenzymatic cascades for organic chemistry has gained much importance in fundamental and industrial research. Moreover, several enzymatic and chemoenzymatic reactions have also served in green and sustainable manufacturing processes especially in fine chemicals, pharmaceutical, and flavor/fragrance industries. Unfortunately, only a few processes have been applied at industrial scale because of the low stabilities of enzymes along with the problematic processes of their recovery and reuse. Immobilization and co-immobilization offer an ideal solution to these problems. This review gives an overview of all the pathways for enzyme immobilization and their use in integrated enzymatic and chemoenzymatic processes in cascade or in a one-pot concomitant execution. We place emphasis on the factors that must be considered to understand the process of immobilization. A better understanding of this fundamental process is an essential tool not only in the choice of the best route of immobilization but also in the understanding of their catalytic activity. |
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