Associação entre tamanho e potencial proliferativo em neurinomas do acústico

Acoustic neuromas are the most common tumors in the cerebellopontine angle. The molecular mechanisms involved in generation and growth of these tumors are not completly elucidated. Many radiological, clinic and imunohistochemystry data were correlated to tumor growth. We studied 11 acoustic neuromas...

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Detalles Bibliográficos
Autores: Tella, Oswaldo Inácio de [UNIFESP], Stávale, João Norberto [UNIFESP], Herculano, Marco Antonio [UNIFESP], Paiva Neto, Manoel Antonio de [UNIFESP], Onishi, Franz Jooji [UNIFESP], Guimarães Filho, Francisco de Assis Vaz [UNIFESP], Silva, Luciano Ricardo França e [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/2973
Acceso en línea:http://dx.doi.org/10.1590/S0004-282X2006000100015
http://repositorio.unifesp.br/handle/11600/2973
Access Level:acceso abierto
Palabra clave:Ki-67
proliferative index
acoustic neuroma
MIB-1
índice proliferativo
neurinoma do acústico
Descripción
Sumario:Acoustic neuromas are the most common tumors in the cerebellopontine angle. The molecular mechanisms involved in generation and growth of these tumors are not completly elucidated. Many radiological, clinic and imunohistochemystry data were correlated to tumor growth. We studied 11 acoustic neuromas surgically treated at Hospital São Paulo/UNIFESP and correlated clinical and radiological data with proliferative index (Ki-67). The size of the tumors were positively correlationated with proliferative index. No other correlation had statistic significativity.

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