HPV infection and endometriosis: a systematic review and meta-analysis
Introduction: Recent research has focused on the role of persistent ascending bacterial infections and sexually transmitted infections (STI) as a factor associated to endometriosis. Indeed, some studies investigated the possible role of HPV in endometriosis, but this topic remains inconclusive. Obje...
| Authors: | , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2019 |
| Country: | Brasil |
| Institution: | Sociedade Brasileira de Doenças Sexualmente Transmissíveis |
| Repository: | DST (Niterói. Online) |
| Language: | English |
| OAI Identifier: | oai:ojs.bjstd.org:article/866 |
| Online Access: | https://www.bjstd.org/revista/article/view/866 |
| Access Level: | Open access |
| Keyword: | papillomaviridae endometriose infecções por papillomavírus doenças sexualmente transmissíveis reação em cadeia da polimerase sondas de DNA de HPV endometriosis papillomavirus infections sexually transmitted diseases PCR DNA probes HPV |
| Summary: | Introduction: Recent research has focused on the role of persistent ascending bacterial infections and sexually transmitted infections (STI) as a factor associated to endometriosis. Indeed, some studies investigated the possible role of HPV in endometriosis, but this topic remains inconclusive. Objective: The present study aims to meta-analyze research that assessed the presence of HPV infection in patients with endometriosis. Methods: MEDLINE, Embase, Scopus, LILACS, Cochrane Library, and OpenGrey were searched until February 10th, 2020. Search terms included “endometriosis” and “HPV” without language restrictions. The combined relative risks and 95% confidence interval (95%CI) were calculated, and heterogeneity was assessed with I-square (I2). Results: Meta-analysis with low heterogeneity found a relative risk of twice as much in women exposed to HPV in relation to the unexposed control. Conclusion: Results indicate that HPV could be a risk factor for developing endometriosis. |
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