Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, 2011/20484-7 and 2015/09080-2) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, 473343/2012-6), Brazil. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (C...

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Bibliographic Details
Authors: Espada, Caroline Ricce, Magalhães, Rubens M., Cruz, Mario C., Machado, Paulo Roberto, Schriefer, Albert, Carvalho, Edgar Marcelino de, Hornillos, Valentín, Alves, João M., Cruz, Angela Kaysel, Coelho, Adriano Cappellazzo, Uliana, Silvia Reni Bortolin
Format: article
Status:Published version
Publication Date:2019
Country:Brasil
Institution:Fundação Oswaldo Cruz (FIOCRUZ)
Repository:Repositório Institucional da FIOCRUZ (ARCA)
Language:English
OAI Identifier:oai:arca.fiocruz.br:icict/35917
Online Access:https://arca.fiocruz.br/handle/icict/35917
Access Level:Open access
Keyword:Leishmania braziliensis
Isolados
Miltefosine
Suscetibilidade
Captação
RNA-seq
Isolates
Susceptibility
Uptake
RNAseq
Description
Summary:Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, 2011/20484-7 and 2015/09080-2) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, 473343/2012-6), Brazil. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001. SRBU is the recipient of a senior researcher scholarship from CNPq. ACC and CRE were fellows supported by FAPESP (2012/14629-5 and 2016/ 23405-4).

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