Tratamento tópico com nanopartículas de prata e Stryphnodendron Adstringens (Mart.) Coville em lesões cervicais: ensaio clínico randomizado

Objective: To assess the feasibility of incorporating technology as a new alternative for treating topics on cervical lesions. Method: This is a randomized, double-blind, controlled clinical trial with a prospective design. During the realization of this study, 43 women were included and divided bet...

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Detalles Bibliográficos
Autores: Nascimento, Cristiane Araújo, Santos, Ana Caroline Melo dos, Silva, Denise Macedo da, Barbosa, Nirliane Ribeiro, Moura, Edilson Leite de, Silva, Veracilda Bezerra da, Balliano, Tatiane Luciano, Figueiredo, Elaine Virginia Martins de Souza, Farias, Karol Fireman de, Pitta , Guilherme Benjamin Brandão
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Institución:Universidade de São Paulo (USP)
Repositorio:Revista da Escola de Enfermagem da USP (Online)
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/232320
Acceso en línea:https://revistas.usp.br/reeusp/article/view/232320
Access Level:acceso abierto
Palabra clave:Squamous Intraepithelial Lesions of the Cervix
Uterine Cervical Neoplasms
Stryphnodendron barbatimam
Phytotherapy
Lesiones Intraepiteliales Escamosas de Cuello Uterino
Neoplasias del Cuello Uterino
Fitoterapia
Lesões Intraepiteliais Escamosas Cervicais
Neoplasias do Colo do Útero
Descripción
Sumario:Objective: To assess the feasibility of incorporating technology as a new alternative for treating topics on cervical lesions. Method: This is a randomized, double-blind, controlled clinical trial with a prospective design. During the realization of this study, 43 women were included and divided between groups A (ointment without silver nanoparticles n = 23) and B (ointment with silver nanoparticles n = 20) clinically healthy and who used the unified health system. Results: There were no significant differences when comparing before and after the use of ointment for IVA test (p = 0.15), Schiller test (p = 0.15), cellular changes (p = 0.47) and microbiological analysis (p = 0.89) through cytology. After use, no adverse reaction was observed in the sample studied. Conclusion: Based on the results identified in this study, identified that the product is safe and does not promote adverse events. Regarding the effectiveness of the product in uterine cervical lesions, it is necessary to continue the study in phase II. Registro de Ensaios Clínicos Brasileiros: UTN: U1111-1218-2820.

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