Opsonization and transformation: effects of anticapsular sera on the DNA transfer in Neisseria meningitidis
The capsular switching process indicates the action of specific capsular antibodies on the meningococcal strains adaptation. Different antibodies were employed for assessing the effect of opsonization on the transformation of Neisseria meningitidis serogroups C and W135. These analyses showed the bl...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Instituto Adolfo Lutz |
| Repositorio: | Revista do Instituto Adolfo Lutz (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:ojs.periodicos.saude.sp.gov.br:article/32472 |
| Acceso en línea: | https://periodicos.saude.sp.gov.br/RIAL/article/view/32472 |
| Access Level: | acceso abierto |
| Palabra clave: | Neisseria meningitidis transformation opsonization capsule transformação opsonização cápsula |
| Sumario: | The capsular switching process indicates the action of specific capsular antibodies on the meningococcal strains adaptation. Different antibodies were employed for assessing the effect of opsonization on the transformation of Neisseria meningitidis serogroups C and W135. These analyses showed the blocking action of the specific capsular antibodies on the meningococcal transformation capacity. Thus, the blocking effect of these antibodies on N. meningitidis transformation process was demonstrated. This effect could be involved in the capsular switching process and the found data might open new subjects for scientific exploration. |
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