Solitary fibrous tumor of the kidney: a report of two cases

ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral...

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Detalles Bibliográficos
Autores: Oliveira,Rui Pedro Caetano M., Silva,Edgar Miguel C. L. T, Marinho,Carol dos Anjos, Lopez,José Ignacio, Castro,Lígia Romana O. A. P.
Tipo de recurso: informe técnico
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Institución:Sociedade Brasileira de Patologia (SBP)
Repositorio:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Idioma:inglés
OAI Identifier:oai:scielo:S1676-24442019000100118
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100118
Access Level:acceso abierto
Palabra clave:solitary fibrous tumors
kidney neoplasms
immunohistochemistry
Descripción
Sumario:ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.