Angiotensin converting enzyme regulates cell proliferation and migration
The angiotensin-I converting enzyme (ACE) plays a central role in the renin-angiotensin system, acting by converting the hormone angiotensin-I to the active peptide angiotensin-II (Ang-II). More recently, ACE was shown to act as a receptor for Ang-II, and its expression level was demonstrated to be...
| Autores: | , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Brasil |
| Institución: | Universidade Federal de Minas Gerais (UFMG) |
| Repositorio: | Repositório Institucional da UFMG |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/50145 |
| Acceso en línea: | https://doi.org/10.1371/journal.pone.0165371 http://hdl.handle.net/1843/50145 https://orcid.org/0000-0002-9480-9761 https://orcid.org/0000-0002-0064-1882 https://orcid.org/0000-0002-4507-632X https://orcid.org/0000-0002-8551-5948 https://orcid.org/0000-0001-9709-8865 https://orcid.org/0000-0001-9048-9775 https://orcid.org/0000-0002-2210-0526 https://orcid.org/0000-0001-7867-3908 |
| Access Level: | acceso abierto |
| Palabra clave: | Ácido ribonucleico Enzimas Angiotensina |
| Sumario: | The angiotensin-I converting enzyme (ACE) plays a central role in the renin-angiotensin system, acting by converting the hormone angiotensin-I to the active peptide angiotensin-II (Ang-II). More recently, ACE was shown to act as a receptor for Ang-II, and its expression level was demonstrated to be higher in melanoma cells compared to their normal counterparts. However, the function that ACE plays as an Ang-II receptor in melanoma cells has not been defined yet. |
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