Evaluation of the short-form 36-item questionnaire to measure health-related quality of life in patients with idiopathic pulmonary fibrosis
Objective: To validate the use of the 36-item short-form questionnaire (SF-36) for measuring health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).Design: Observational data at a single point in time,Setting: A specialized outpatient respiratory clinic.Participan...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2000 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/26316 |
| Acceso en línea: | http://dx.doi.org/10.1378/chest.117.6.1627 http://repositorio.unifesp.br/handle/11600/26316 |
| Access Level: | acceso abierto |
| Palabra clave: | dyspnea idiopathic pulmonary fibrosis lung function quality of life |
| Sumario: | Objective: To validate the use of the 36-item short-form questionnaire (SF-36) for measuring health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).Design: Observational data at a single point in time,Setting: A specialized outpatient respiratory clinic.Participants: Thirty-four patients (mean +/- SE age, 58.29 +/- 1.87 years) with IPF and no significant comorbidity. A matched control group for HRQL measurements was composed of 34 normal subjects (mean age, 58.00 +/- 1.89 years).Measurements and results: Dyspnea was measured by the baseline dyspnea index (BDI). Respiratory function evaluation included FVC, FEV1, and resting; arterial blood gases. IPF patients showed a mean BDI score of 5.21 +/- 0.46. the mean FVC and FEV1 values were 62.41 +/- 2.96% and 66.41 +/- 3.33%, respectively. the mean Pao(2) was 67 +/- 2.51 mm Hg, and the mean Paco(2) was 37 +/- 1.05 mm Hg. Patients scored significantly worse than control subjects with respect to the SF-36 domains of physical functioning, physical role, general health perceptions, vitality, social functioning, emotional role, and mental health index. BDI scores were significantly correlated with five SF-36 components, and FVC and FEV1 were significantly correlated with two SF-36 components. Significant negative correllations were found between arterial pH and four SF-36 domains.Conclusions: Patients with IPF have a significant impairment of HRQL in both physical and psychological functioning. Dyspnea is the most important factor influencing the quality of life in these subjects. the SF-36 questionnaire is a valid instrument to evaluate HRQL in IPF patients. |
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