Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum

Essential oil of cinnamon (Cinnamomum zeylanicum) has been used in medicine and food additives. In the present work, we examined the antifungal activity of essential oil extracted from C. zeylanicum bark against oral opportunistic strains of Candida albicans. In addition, we verified the capability...

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Autores: Priscila Codeiro de Lima Carvalho, Nívea Pereira de Sá, Inayara Cristina Alves Lacerda, Carla Pataro, Luiz Henrique Rosa, Rodrigo Silva Alves, Juliana Pereira Lyon, Carlos Augusto Rosa, Susana Johann
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Federal de Minas Gerais (UFMG)
Repositorio:Repositório Institucional da UFMG
Idioma:inglés
OAI Identifier:oai:repositorio.ufmg.br:1843/40919
Acceso en línea:http://hdl.handle.net/1843/40919
Access Level:acceso abierto
Palabra clave:Adhesion
Cinnamon oil
Germ tube
Proteinase
Plantas medicinais
Canela
Cinnamomum zeylanicum
Óleo essencial
Candida albicans
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spelling Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicumAdhesionCinnamon oilGerm tubeProteinasePlantas medicinaisCanelaCinnamomum zeylanicumÓleo essencialCandida albicansEssential oil of cinnamon (Cinnamomum zeylanicum) has been used in medicine and food additives. In the present work, we examined the antifungal activity of essential oil extracted from C. zeylanicum bark against oral opportunistic strains of Candida albicans. In addition, we verified the capability of this essential oil to inhibit fungal adhesion to buccal epithelial cells (BECs), germ tube formation, and proteinase activities. Cinnamon oil presented minimum inhibitory concentration (MIC) values that ranged from 31.2 to 125 µg mL-1 against the isolates of the tested C. albicans strains. Cinnamon essential oil could inhibit the adhesion of C. albicans to BECs for all of the isolates tested in present study. The C. albicans strains showed inhibited proteinase production after treatment with cinnamon oil, based on the MIC values determined for each C. albicans strain. Cinnamon oil was also able to inhibit the germ tube formation of all isolates of C. albicans, with the percentage of inhibition ranging from 44.7 to 82.9%. Our results showed that cinnamon oil presented potent antifungal activity and the ability to inhibit virulence factors of oral pathogenic strains of C. albicans.Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE ALIMENTOSICB - DEPARTAMENTO DE MICROBIOLOGIAUFMG2022-04-08T00:30:12Z2022-04-08T00:30:12Z2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdf2518-3834http://hdl.handle.net/1843/40919engPSM Microbiologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGPriscila Codeiro de Lima CarvalhoNívea Pereira de SáInayara Cristina Alves LacerdaCarla PataroLuiz Henrique RosaRodrigo Silva AlvesJuliana Pereira LyonCarlos Augusto RosaSusana Johann2022-04-08T00:30:12Zoai:repositorio.ufmg.br:1843/40919Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2022-04-08T00:30:12Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
title Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
spellingShingle Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
Priscila Codeiro de Lima Carvalho
Adhesion
Cinnamon oil
Germ tube
Proteinase
Plantas medicinais
Canela
Cinnamomum zeylanicum
Óleo essencial
Candida albicans
title_short Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
title_full Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
title_fullStr Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
title_full_unstemmed Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
title_sort Anti-candida activity of cinnamon inhibition of virulence factors of clinical strains of Candida albicans by essential oil of Cinnamomum zeylanicum
dc.creator.none.fl_str_mv Priscila Codeiro de Lima Carvalho
Nívea Pereira de Sá
Inayara Cristina Alves Lacerda
Carla Pataro
Luiz Henrique Rosa
Rodrigo Silva Alves
Juliana Pereira Lyon
Carlos Augusto Rosa
Susana Johann
author Priscila Codeiro de Lima Carvalho
author_facet Priscila Codeiro de Lima Carvalho
Nívea Pereira de Sá
Inayara Cristina Alves Lacerda
Carla Pataro
Luiz Henrique Rosa
Rodrigo Silva Alves
Juliana Pereira Lyon
Carlos Augusto Rosa
Susana Johann
author_role author
author2 Nívea Pereira de Sá
Inayara Cristina Alves Lacerda
Carla Pataro
Luiz Henrique Rosa
Rodrigo Silva Alves
Juliana Pereira Lyon
Carlos Augusto Rosa
Susana Johann
author2_role author
author
author
author
author
author
author
author
dc.subject.por.fl_str_mv Adhesion
Cinnamon oil
Germ tube
Proteinase
Plantas medicinais
Canela
Cinnamomum zeylanicum
Óleo essencial
Candida albicans
topic Adhesion
Cinnamon oil
Germ tube
Proteinase
Plantas medicinais
Canela
Cinnamomum zeylanicum
Óleo essencial
Candida albicans
description Essential oil of cinnamon (Cinnamomum zeylanicum) has been used in medicine and food additives. In the present work, we examined the antifungal activity of essential oil extracted from C. zeylanicum bark against oral opportunistic strains of Candida albicans. In addition, we verified the capability of this essential oil to inhibit fungal adhesion to buccal epithelial cells (BECs), germ tube formation, and proteinase activities. Cinnamon oil presented minimum inhibitory concentration (MIC) values that ranged from 31.2 to 125 µg mL-1 against the isolates of the tested C. albicans strains. Cinnamon essential oil could inhibit the adhesion of C. albicans to BECs for all of the isolates tested in present study. The C. albicans strains showed inhibited proteinase production after treatment with cinnamon oil, based on the MIC values determined for each C. albicans strain. Cinnamon oil was also able to inhibit the germ tube formation of all isolates of C. albicans, with the percentage of inhibition ranging from 44.7 to 82.9%. Our results showed that cinnamon oil presented potent antifungal activity and the ability to inhibit virulence factors of oral pathogenic strains of C. albicans.
publishDate 2018
dc.date.none.fl_str_mv 2018
2022-04-08T00:30:12Z
2022-04-08T00:30:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv 2518-3834
http://hdl.handle.net/1843/40919
identifier_str_mv 2518-3834
url http://hdl.handle.net/1843/40919
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PSM Microbiology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FAR - DEPARTAMENTO DE ALIMENTOS
ICB - DEPARTAMENTO DE MICROBIOLOGIA
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FAR - DEPARTAMENTO DE ALIMENTOS
ICB - DEPARTAMENTO DE MICROBIOLOGIA
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
_version_ 1853663172303519744
score 15.301603

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