Mortality of older adults with community-acquired respiratory infections associated with sepsis in the Intensive Care Unit

Background and Objectives: Infections in older adults are more frequent and severe, and can lead to sepsis, an immediate cause of death in the intensive care unit (ICU). This study aimed to identify risk factors associated with the death of elderly patients with sepsis who were admitted to the ICU d...

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Detalles Bibliográficos
Autores: Weigert, Fernanda, Oles, Helena, Palogan Reginato, Caroline, Vicente Muller, Erildo, Carolina Pacheco, Elis, Ivastcheschen Taques, Taís, Kassia de Oliveira Borges, Pollyana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:Brasil
Institución:Universidade de Santa Cruz do Sul (UNISC)
Repositorio:Revista de Epidemiologia e Controle de Infecção
Idioma:portugués
inglés
OAI Identifier:oai:ojs.online.unisc.br:article/20017
Acceso en línea:https://seer.unisc.br/index.php/epidemiologia/article/view/20017
Access Level:acceso abierto
Palabra clave:Hospital mortality
Sepsis
Aged
Mortalidad hospitalaria
Anciano
Mortalidade hospitalar
Sepse
Idoso
Descripción
Sumario:Background and Objectives: Infections in older adults are more frequent and severe, and can lead to sepsis, an immediate cause of death in the intensive care unit (ICU). This study aimed to identify risk factors associated with the death of elderly patients with sepsis who were admitted to the ICU due to a previous community-acquired respiratory infection. Methods: This is an epidemiological, descriptive, and analytical study of a mixed cohort. The medical records of older adults admitted to the ICU from September 2019 to September 2020 with a diagnosis of a community-acquired respiratory infection who died due to sepsis were analyzed according to the presence or absence of SARS-CoV-2 infection. Sociodemographic and clinical data were collected. Descriptive and statistical analyses were performed. Results: Most patients were male and between 60 and 79 years old. Having chronic respiratory disease (RR = 1.9; p = 0.014) and a viral etiology (RR = 3.2; p < 0.001) were associated with death. Conclusion: These results reinforce the importance of preventing respiratory diseases in the older adults community and of early intervention to avoid deterioration and death.