Experimental model in hamster (Mesocricetus auratus) to study heterologous graft of scars and cutaneous diseases in plastic surgery
Syrian golden hamster (Mesocricetus auratus) has in its cheek pouches sub-epithelium an Immunologically Privileged Site which allows the integration of homo- and heterologous graft. This paper describes some anatomical and histological characteristics of that site, as well as analyzes aspects relate...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2004 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/2305 |
| Acceso en línea: | http://dx.doi.org/10.1590/S0102-86502004000700013 http://repositorio.unifesp.br/handle/11600/2305 |
| Access Level: | acceso abierto |
| Palabra clave: | Mesocricetus Transplantation, heterologous Skin transplantation Keloid Transplante heterólogo Transplante de pele Quelóide |
| Sumario: | Syrian golden hamster (Mesocricetus auratus) has in its cheek pouches sub-epithelium an Immunologically Privileged Site which allows the integration of homo- and heterologous graft. This paper describes some anatomical and histological characteristics of that site, as well as analyzes aspects related with its immune properties. It also focuses the advantages of this experimental model over other models which are natural or induced carriers of immunodeficiency. Based on both these advantages and literature, this study aims to establish this model, through the performance of heterologous graft, as another option for the investigation of scar disturbances, as keloids and other diseases which may interest Plastic Surgery, as benign cutaneous lesions, and malignant neoplasias such as skin carcinomas and melanomas. The work also addresses perspectives for using this model, which still is a source scarcely known by Brazilian medical class. |
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