Papilomatose de laringe
Laryngeal papillomatosis is the most frequent benign neoplasm of the larynx, occurring in children and adults. It is caused by the human papilloma virus, especially types 6 and 11. The clinical course is unpredictable and recurrence is frequent in children. There have been reports of association bet...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | Brasil |
| Institución: | Universidade Federal do Rio Grande do Sul (UFRGS) |
| Repositorio: | Clinical and Biomedical Research |
| Idioma: | portugués |
| OAI Identifier: | oai:seer.ufrgs.br:article/125224 |
| Acceso en línea: | https://seer.ufrgs.br/index.php/hcpa/article/view/125224 |
| Access Level: | acceso abierto |
| Palabra clave: | Papilomatose laríngea papiloma vírus humano (HPV) laser CO2 tratamento adjuvante Laryngeal papillomatosis human papilloma virus (HPV) carbon dioxide laser adjuvant treatment |
| Sumario: | Laryngeal papillomatosis is the most frequent benign neoplasm of the larynx, occurring in children and adults. It is caused by the human papilloma virus, especially types 6 and 11. The clinical course is unpredictable and recurrence is frequent in children. There have been reports of association between this disease and tracheobronchial tree and squamous cell carcinoma of the larynx. Papillomatosis is probably one of thefactors that can predispose a patient to the development of cancer, similarly to alcohol, tobacco, and radiation exposure.Treatment aims at maintaining airway patency and speech. Surgery with carbon dioxide laser is able to achieve this objective, however, without preventing recidivation. The low rates of surgical cure have been stimulating new research with chemotherapics. Unfortunately these have not been successful. Their main purpose is to reduce the extension of the disease and rates of recidivation, slowing down papilloma growth.The present study reviews pathophysiology, the clinical presentation and treatment aspects . |
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