Embryos refrozen-thawed by vitrification lead to live births: Case report

Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary...

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Detalles Bibliográficos
Autores: Mauri, Ana L., Petersen, Claudia G., Oliveira, João B.A. [UNESP], Baruffi, Ricardo L.R., Al-Hasani, Saffa, Franco Junior, Jose Gonçalves [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/72316
Acceso en línea:http://dx.doi.org/10.1016/j.mefs.2010.09.008
http://hdl.handle.net/11449/72316
Access Level:acceso abierto
Palabra clave:Cryopreservation
Frozen embryo transfer
Refrozen embryos
Vitrification
adult
blastocyst
case report
cell cycle phase
cell viability
clinical protocol
cryopreservation
density gradient centrifugation
embryo culture
embryo transfer
female
female infertility
fertilization in vitro
freeze thawing
human
intermethod comparison
live birth
medical history
phase transition
pregnancy outcome
repeat procedure
vitrification
Descripción
Sumario:Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular. © 2010 Middle East Fertility Society.