Efficacy of medical grade honey in the treatment of diabetic foot ulcers: a systematic review

Objective: To analyze the effectiveness of medical grade honey in the treatment of diabetic foot ulcers. Methodology: This is a systematic review carried out using the PRISMA method, in the electronic databases PubMed, Scopus and Web of Science, using the following descriptors: “honey”, “wound”, “wo...

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Bibliographic Details
Authors: Nascimento, José William Araújo do, Roque, Geicianfran da Silva Lima, Thorpe, Lucia Ingridy Farias, Morais, Talita das Neves de, Santana, Fernanda Suely Fontes de Souza, Silva, Eduardo Fernando Gomes Cavalcanti da, Oliveira, Samanta Alves Ramos de, Silva Neto, Gerson Waltrudes da, Santana, Jéssica Lucas de, Conceição, Dário César de Oliveira
Format: article
Status:Published version
Publication Date:2022
Country:Brasil
Institution:Universidade Federal de Itajubá (UNIFEI)
Repository:Research, Society and Development
Language:Portuguese
OAI Identifier:oai:ojs.pkp.sfu.ca:article/27839
Online Access:https://rsdjournal.org/index.php/rsd/article/view/27839
Access Level:Open access
Keyword:Wound healing
Wounds and injuries
Honey.
Cicatrización de heridas
Heridas y lesiones
Miel.
Cicatrização de feridas
Ferimentos e lesões
Mel.
Description
Summary:Objective: To analyze the effectiveness of medical grade honey in the treatment of diabetic foot ulcers. Methodology: This is a systematic review carried out using the PRISMA method, in the electronic databases PubMed, Scopus and Web of Science, using the following descriptors: “honey”, “wound”, “wound healing”, “honey dressing” and “diabetic foot”. Full articles, available in Portuguese, English and Spanish, published between January 2010 and December 2020, research conducted in humans and studies focusing on honey in the treatment of diabetic foot ulcers were included. Results: Seven articles made up the final sample of this study, with the highest production in China (n: 03). All studies used the Randomized Clinical Trial methodology, characterizing the studies as presenting a strong level of evidence (II). The treatment of diabetic foot ulcers with honey was found to have good overall efficacy, such that four studies had higher healing rates compared to their respective control groups and shorter healing times. It was found that the results presented suggested that the honey dressing was associated with a higher rate and earlier bacterial clearance time compared to other dressings. Conclusion: It was found that medical grade honey was effective in the treatment of diabetic foot ulcers, promoting high healing rates in a shorter period and high bacterial load reduction. However, some coverages used as controls showed greater efficacy, prompting more robust studies for a greater generalization of the results.

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