Radioisotopic perfusional assessment of blood circulation changes in skin under progressive expansion: experimental model with rabbits

The purpose of this experimental model with rabbits is investigating the variation of blood flow in the expanded skin versus expansion time. New Zealand breed rabbits are used. Two groups are studied: F-1 receiving expanders on the right tight and F-2 receiving expanders bilateraly. Progressively, f...

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Bibliographic Details
Authors: Horibe, Edith Kawano [UNIFESP], Horibe, Kose
Format: article
Status:Published version
Publication Date:2004
Country:Brasil
Institution:Universidade Federal de São Paulo (UNIFESP)
Repository:Repositório Institucional da UNIFESP
Language:English
OAI Identifier:oai:repositorio.unifesp.br:11600/2308
Online Access:http://dx.doi.org/10.1590/S0102-86502004000700015
http://repositorio.unifesp.br/handle/11600/2308
Access Level:Open access
Keyword:Perfusion
Radioisotopes
Skin
Tissue expansion
Model Animal
Rabbit
Perfusão
Radioisotópos
Expansão de Tecido
Pele
Modelo Animal
Coelho
Description
Summary:The purpose of this experimental model with rabbits is investigating the variation of blood flow in the expanded skin versus expansion time. New Zealand breed rabbits are used. Two groups are studied: F-1 receiving expanders on the right tight and F-2 receiving expanders bilateraly. Progressively, five expansions are performed. The first radioiosotopic perfusional evaluation is performed just after the surgery and the following evaluation are performed at the second, sixth, thirteenth, twentieth and twenty-seventh post-surgical days. As radiotracer, technetium 99m are used in the chemical form of sodium pertechnetate. Scintillographic images are obtained by CGR scintillation camera. The quantitative analysis is done by calculation of the reperfusion rate.