Comparação entre as técnicas pré-tarsal e pré-septal na aplicação de toxina botulínica em blefaroespasmo e espasmo hemifacial

Botulinum toxin has a well-reported efficacy in the treatment of blepharospasm and hemifacial spasm, portraying B and C level of recommendation, respectively. In spite of this clear benefit, only a few studies compared the many injection techniques available in the literature and different protocols...

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Detalles Bibliográficos
Autor: Daniel Resende Carvalho Sacramento
Tipo de recurso: tesis de maestría
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Federal de Minas Gerais (UFMG)
Repositorio:Repositório Institucional da UFMG
Idioma:portugués
OAI Identifier:oai:repositorio.ufmg.br:1843/BUOS-B3XMDM
Acceso en línea:http://hdl.handle.net/1843/BUOS-B3XMDM
Access Level:acceso abierto
Palabra clave:Prétarsal
Blefaroespasmo
Espasmo hemifacial
Toxina botulínica
Pré-septal
Blefarospasmo
Neurociências
Espasmo Hemifacial
Toxinas Botulínicas
Descripción
Sumario:Botulinum toxin has a well-reported efficacy in the treatment of blepharospasm and hemifacial spasm, portraying B and C level of recommendation, respectively. In spite of this clear benefit, only a few studies compared the many injection techniques available in the literature and different protocols lack proper supporting scientific evidence. The present study was then designed to longitudinally compare the pretarsal and preseptal techniques of one hundred and ten patients with blepharospasm and hemifacial spasm. Analysis of seven different scales showed no difference between these techniques neither on maximal effect nor on side effects profiles. However, a significantly longer therapeutic effect duration of the pretarsal was found and a subjective inquiry reported by the patients indicated a preference for the same one. Our data are in agreement with previous studies that suggested that the pretarsal technique may be a better therapeutic option