Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil

A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban population of all Brazilian state capitals and the Federal District, between 2005 and 2009. This paper describes the design and methodology of...

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Detalles Bibliográficos
Autores: Ximenes, Ricardo Arraes de Alencar, Pereira, Leila Maria Beltrão, Martelli, Celina Maria Turchi, Merchán-Hamann, Edgar, Stein, Airton Tetelbom, Figueiredo, Gerusa Maria, Braga, Maria Cynthia, Montarroyos, Ulisses Ramos, Brasil, Leila Melo, Turchi, Marília Dalva, Fonseca, José Carlos Ferraz da, Lima, Maria Luiza Carvalho de, Alencar, Luis Cláudio Arraes de, Costa, Marcelo, Coral, Gabriela, Moreira, Regina Celia, Cardoso, Maria Regina Alves
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Cadernos de Saúde Pública
Idioma:inglés
OAI Identifier:oai:ojs.teste-cadernos.ensp.fiocruz.br:article/4229
Acceso en línea:https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4229
Access Level:acceso abierto
Palabra clave:Morbidity Surveys
Prevalence
Hepatitis Viruses
Descripción
Sumario:A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban population of all Brazilian state capitals and the Federal District, between 2005 and 2009. This paper describes the design and methodology of the study which involved a population aged 5 to 19 for hepatitis A and 10 to 69 for hepatitis B and C. Interviews and blood samples were obtained through household visits. The sample was selected using stratified multi-stage cluster sampling and was drawn with equal probability from each domain of study (region and age-group). Nationwide, 19,280 households and ~31,000 residents were selected. The study is large enough to detect prevalence of viral infection around 0.1% and risk factor assessments within each region. The methodology seems to be a viable way of differentiating between distinct epidemiological patterns of hepatitis A, B and C. These data will be of value for the evaluation of vaccination policies and for the design of control program strategies.