Diagnosis of hyperprolactinemia in women: A Position Statement from the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and the Brazilian Society of Endocrinology and Metabolism (SBEM)

Hyperprolactinemia is a frequent cause of menstrual irregularity, galactorrhea, hypogonadism, and infertility. The most common etiologies of hyperprolactinemia can be classified as physiological, pharmacological, and pathological. Among pathological conditions, it is essential to distinguish prolact...

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Detalles Bibliográficos
Autores: Glezer, Andrea, Garmes, Heraldo Mendes, Kasuki, Leandro, Martins, Manoel, Elias, Paula Condé Lamparelli, Nogueira, Vania dos Santos Nunes [UNESP], de Sá Rosa-E-Silva, Ana Carolina Japur, Maciel, Gustavo Arantes Rosa, Benetti-Pinto, Cristina Laguna, Nácul, Andrea Prestes
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/296873
Acceso en línea:http://dx.doi.org/10.20945/2359-4292-2023-0502
https://hdl.handle.net/11449/296873
Access Level:acceso abierto
Palabra clave:hook effect
hyperprolactinemia
macroprolactin
pituitary tumor
Prolactinoma
Descripción
Sumario:Hyperprolactinemia is a frequent cause of menstrual irregularity, galactorrhea, hypogonadism, and infertility. The most common etiologies of hyperprolactinemia can be classified as physiological, pharmacological, and pathological. Among pathological conditions, it is essential to distinguish prolactinomas from other tumors and pituitary lesions presenting with hyperprolactinemia due to pituitary stalk disconnection. Proper investigation considering clinical data, laboratory tests, and, if necessary, imaging evaluation, is important to identify the correct cause of hyperprolactinemia and manage the patient properly. This position statement by the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and Brazilian Society of Endocrinology and Metabolism (SBEM) addresses the recommendations for measurement of serum prolactin levels and the investigations of symptomatic and asymptomatic hyperprolactinemia and medication-induced hyperprolactinemia in women.