The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?

Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally,...

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Detalles Bibliográficos
Autores: Albuquerque, Marly de [UNIFESP], Scorza, Carla Alessandra [UNIFESP], Arida, Ricardo Mario [UNIFESP], Cavalheiro, Esper Abrão [UNIFESP], Scorza, Fulvio Alexandre [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/5020
Acceso en línea:http://dx.doi.org/10.1590/S0004-282X2009000300038
http://repositorio.unifesp.br/handle/11600/5020
Access Level:acceso abierto
Palabra clave:epilepsy
Gustave Flaubert
SUDEP
seizure
epilepsia
crise epiléptica
Descripción
Sumario:Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. More than two decades ago, temporal lobe epilepsy was suggested as having been the ''nervous disease'' of Gustave Flaubert, one of the most important French novelists. In these lines, as the circumstances of his death were the subject of fabulous and mysterious speculations, we postulated in this paper that Falubert' death could be due SUDEP phenomenon.