Identification of a new clade of hepatitis B virus genotype F

Hepatitis B virus (HBV) is classified into eight main genotypes (A–H) and several subgenotypes. Here, three new genotype F complete genome sequences isolated from patients from Buenos Aires city are reported. The new sequences form a separate monophyletic group from the previously known subgenotype...

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Detalles Bibliográficos
Autores: Mojsiejczuk, Laura Noelia, Torres, Carolina, Fainboin, Hugo Alberto, Galdame, Omar Andrés, Campos, Rodolfo Hector, Flichman, Diego Martin
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/15968
Acceso en línea:http://hdl.handle.net/11336/15968
Access Level:acceso abierto
Palabra clave:Diversity
Evolution
Hbv Genotype F
Hepatitis B Virus
Phylogenetics
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Descripción
Sumario:Hepatitis B virus (HBV) is classified into eight main genotypes (A–H) and several subgenotypes. Here, three new genotype F complete genome sequences isolated from patients from Buenos Aires city are reported. The new sequences form a separate monophyletic group from the previously known subgenotype F4 strains. Based on results of phylogenetic, genetic distance and evolutionary analyses, the name F4b is proposed for these isolates and F4a for the formerly known as F4. The identification of new clusters allows deepening the knowledge about the diversification process and evolutionary history of HBV.