Synthesis of Carbolines by Photostimulated Cyclization of Anilinohalopyridines

A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the S(RN)1 methodology complements previously rep...

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Detalles Bibliográficos
Autores: Laha, Joydev K., Barolo, Silvia Maricel, Rossi, Roberto Arturo, Cuny, Gregory D.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/66183
Acceso en línea:http://hdl.handle.net/11336/66183
Access Level:acceso abierto
Palabra clave:Srn1
Carbolines
Photochemistry
Ring Closure
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the S(RN)1 methodology complements previously reported palladium-catalyzed cyclization approaches.