Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens

Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNP...

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Bibliographic Details
Authors: Zanetti, Flavia Adriana, Conte Grand, María Daniela, Mitarotonda, Romina Cristina, Taboga, Oscar Alberto, Calamante, Gabriela
Format: article
Status:Published version
Publication Date:2014
Country:Argentina
Institution:Instituto Nacional de Tecnología Agropecuaria
Repository:INTA Digital (INTA)
Language:English
OAI Identifier:oai:localhost:20.500.12123/3578
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059302/
http://hdl.handle.net/20.500.12123/3578
http://dx.doi.org/10.1590/S1517-83822014000100032
Access Level:Open access
Keyword:Virus bursitis infecciosa
Pollo
Anticuerpos
Infectious bursal disease virus
Chickens
Antibodies
Canarypox Virus
Proteína VP2
VP2 Protein
Description
Summary:Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNPV platform is usefulness to develop immunogens for chickens.