Plasmonic Mesoporous Composites as Molecular Sieves for SERS Detection
Application of surface-enhanced Raman scattering (SERS) spectroscopy to the ultrasensitive analysis of small molecules in biological samples is complicated by signal contamination by ubiquitous macromolecules such as proteins, nucleic acids, or lipids. We present a proof-of-concept study of the appl...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2013 |
| País: | Argentina |
| Recursos: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/3211 |
| Acesso em linha: | http://hdl.handle.net/11336/3211 |
| Access Level: | acceso abierto |
| Palavra-chave: | Mesoporous Tio2 Thin Films Sers Sensors https://purl.org/becyt/ford/2.10 https://purl.org/becyt/ford/2 |
| Resumo: | Application of surface-enhanced Raman scattering (SERS) spectroscopy to the ultrasensitive analysis of small molecules in biological samples is complicated by signal contamination by ubiquitous macromolecules such as proteins, nucleic acids, or lipids. We present a proof-of-concept study of the application of composite films comprising branched gold nanoparticles embedded in mesoporous thin films, which act as molecular sieves. The inorganic mesoporous layer only allows the diffusion of small molecules toward the plasmonic particles while preventing the contact of macromolecules in solution with the optical sensor. |
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