Life at the edge: Complexity and criticality in biological function

Why life is complex and - most importantly - what is the origin of the over abundance of complexity in nature? This is a fundamental scientific question which, paraphrasing the late Per Bak, “is screaming to be answered but seldom is even being asked”. In this article, we review recent attempts acro...

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Detalles Bibliográficos
Autor: Chialvo, Dante Renato
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/98305
Acceso en línea:http://hdl.handle.net/11336/98305
Access Level:acceso abierto
Palabra clave:complexity
criticality
biology
life
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
Descripción
Sumario:Why life is complex and - most importantly - what is the origin of the over abundance of complexity in nature? This is a fundamental scientific question which, paraphrasing the late Per Bak, “is screaming to be answered but seldom is even being asked”. In this article, we review recent attempts across several scales to understand the origins of complex biological problems from the perspective of critical phenomena. To illustrate the approach, three cases are discussed, namely the large scale brain dynamics, the characterization of spontaneous fluctuations of proteins, and the physiological complexity of the cell mitochondria network.