Galectins in angiogenesis: Consequences for gestation

Members of the galectin family have been shown to exert several roles in the context of reproduction. They contribute to placentation, maternal immune regulation and facilitate angiogenesis encompassing decidualisation and placenta formation during pregnancy. In the context of neo-vascularisation, g...

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Autores: Blois, Sandra M., Conrad, Melanie L., Freitag, Nancy, Barrientos, Gabriela Laura
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/38397
Acceso en línea:http://hdl.handle.net/11336/38397
Access Level:acceso abierto
Palabra clave:Angiogenesis
Galectins
Pregnancy
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
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spelling Galectins in angiogenesis: Consequences for gestationBlois, Sandra M.Conrad, Melanie L.Freitag, NancyBarrientos, Gabriela LauraAngiogenesisGalectinsPregnancyhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Members of the galectin family have been shown to exert several roles in the context of reproduction. They contribute to placentation, maternal immune regulation and facilitate angiogenesis encompassing decidualisation and placenta formation during pregnancy. In the context of neo-vascularisation, galectins have been shown to augment signalling pathways that lead to endothelial cell activation, cell proliferation, migration and tube formation in vitro in addition to angiogenesis in vivo. Angiogenesis during gestation ensures not only proper foetal growth and development, but also maternal health. Consequently, restriction of placental blood flow has major consequences for both foetus and mother, leading to pregnancy diseases. In this review we summarise both the established and the emerging roles of galectin in angiogenesis and discuss the possible implications during healthy and pathological gestation.Fil: Blois, Sandra M.. Universitätsmedizin Berlin. Charité-Center; AlemaniaFil: Conrad, Melanie L.. Universitätsmedizin Berlin. Charité-Center; AlemaniaFil: Freitag, Nancy. Universitätsmedizin Berlin. Charité-Center; AlemaniaFil: Barrientos, Gabriela Laura. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier Ireland2015-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/38397Blois, Sandra M.; Conrad, Melanie L.; Freitag, Nancy; Barrientos, Gabriela Laura; Galectins in angiogenesis: Consequences for gestation; Elsevier Ireland; Journal of Reproductive Immunology; 108; 4-2015; 33-410165-0378CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165037814001600info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jri.2014.12.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:32:47Zoai:ri.conicet.gov.ar:11336/38397instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:32:47.885CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Galectins in angiogenesis: Consequences for gestation
title Galectins in angiogenesis: Consequences for gestation
spellingShingle Galectins in angiogenesis: Consequences for gestation
Blois, Sandra M.
Angiogenesis
Galectins
Pregnancy
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
title_short Galectins in angiogenesis: Consequences for gestation
title_full Galectins in angiogenesis: Consequences for gestation
title_fullStr Galectins in angiogenesis: Consequences for gestation
title_full_unstemmed Galectins in angiogenesis: Consequences for gestation
title_sort Galectins in angiogenesis: Consequences for gestation
dc.creator.none.fl_str_mv Blois, Sandra M.
Conrad, Melanie L.
Freitag, Nancy
Barrientos, Gabriela Laura
author Blois, Sandra M.
author_facet Blois, Sandra M.
Conrad, Melanie L.
Freitag, Nancy
Barrientos, Gabriela Laura
author_role author
author2 Conrad, Melanie L.
Freitag, Nancy
Barrientos, Gabriela Laura
author2_role author
author
author
dc.subject.none.fl_str_mv Angiogenesis
Galectins
Pregnancy
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
topic Angiogenesis
Galectins
Pregnancy
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
description Members of the galectin family have been shown to exert several roles in the context of reproduction. They contribute to placentation, maternal immune regulation and facilitate angiogenesis encompassing decidualisation and placenta formation during pregnancy. In the context of neo-vascularisation, galectins have been shown to augment signalling pathways that lead to endothelial cell activation, cell proliferation, migration and tube formation in vitro in addition to angiogenesis in vivo. Angiogenesis during gestation ensures not only proper foetal growth and development, but also maternal health. Consequently, restriction of placental blood flow has major consequences for both foetus and mother, leading to pregnancy diseases. In this review we summarise both the established and the emerging roles of galectin in angiogenesis and discuss the possible implications during healthy and pathological gestation.
publishDate 2015
dc.date.none.fl_str_mv 2015-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/38397
Blois, Sandra M.; Conrad, Melanie L.; Freitag, Nancy; Barrientos, Gabriela Laura; Galectins in angiogenesis: Consequences for gestation; Elsevier Ireland; Journal of Reproductive Immunology; 108; 4-2015; 33-41
0165-0378
CONICET Digital
CONICET
url http://hdl.handle.net/11336/38397
identifier_str_mv Blois, Sandra M.; Conrad, Melanie L.; Freitag, Nancy; Barrientos, Gabriela Laura; Galectins in angiogenesis: Consequences for gestation; Elsevier Ireland; Journal of Reproductive Immunology; 108; 4-2015; 33-41
0165-0378
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165037814001600
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jri.2014.12.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Ireland
publisher.none.fl_str_mv Elsevier Ireland
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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