Changing epidemiology of hepatitis C virus genotypes in the central region of Argentina

The aim of this study was to analyze the prevalence of hepatitis C virus (HCV) genotypes in Córdoba province, Argentina, over a 12-year period and to study the changes at the molecular level. The HCV genotype was determined in 357 HCV-infected patients, and the phylogeny and demographic reconstructi...

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Detalles Bibliográficos
Autores: Di Lello, Federico Alejandro, Farias, Adrián Alejandro, Culasso, Andrés Carlos Alberto, Pérez, Paula Soledad, Pisano, María Belén, Contigiani, Marta Silvia, Campos, Rodolfo Hector, Ré, Viviana Elizabeth
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/15893
Acceso en línea:http://hdl.handle.net/11336/15893
Access Level:acceso abierto
Palabra clave:Hepatitis C Virus
Genotype
Phylogeny
Argentina
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
Descripción
Sumario:The aim of this study was to analyze the prevalence of hepatitis C virus (HCV) genotypes in Córdoba province, Argentina, over a 12-year period and to study the changes at the molecular level. The HCV genotype was determined in 357 HCV-infected patients, and the phylogeny and demographic reconstruction for HCV-1 was assessed. A significant reduction in HCV-2 prevalence with respect to HCV-1 in Córdoba after 2003 was observed. These findings are consistent with the epidemiological changes observed in South America. Nevertheless, the consequences of these changes remain to be elucidated.

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