A New Approach for Nonlinear Multivariable Fed-Batch Bioprocess Trajectory Tracking Control

This paper proposes a new control law based on linear algebra. This technique allows nonlinear path tracking in multivariable and complex systems. This new methodology consists in finding the control action to make the system follow predefined concentration profiles solving a system of linear equati...

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Bibliographic Details
Authors: Fernández Puchol, María Cecilia, Rómoli, Santiago, Pantano, Maria Nadia, Ortiz, Oscar Alberto, Patiño, Héctor Daniel, Scaglia, Gustavo Juan Eduardo
Format: article
Status:Published version
Publication Date:2017
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/69160
Online Access:http://hdl.handle.net/11336/69160
Access Level:Open access
Keyword:Fed-Batch Fermentation
Nonlinear Control
Penicillin Production
Profiles Tracking Control
https://purl.org/becyt/ford/2.2
https://purl.org/becyt/ford/2
Description
Summary:This paper proposes a new control law based on linear algebra. This technique allows nonlinear path tracking in multivariable and complex systems. This new methodology consists in finding the control action to make the system follow predefined concentration profiles solving a system of linear equations. The controller parameters are selected with a Monte Carlo algorithm so as to minimize a previously defined cost index. The control scheme is applied to a fed-batch penicillin production process. Different tests are shown to prove the controller effectiveness, such as adding parametric uncertainty, perturbations in the control action and in the initial conditions. Moreover, a comparison with other controllers from the literature is made, showing the better performance of the present approach.