Synthesis and computational simulation of new phosphorilated sulfoximines with insecticidal activity
New organophosphorus insecticides of dialkylsulphoximines derived with activity upon acetylcholinesterase were synthesized. The obtained compounds were characterized by NMR and IR, and anticholinesterase activity and toxicity was measured. A simulation through computer was done in order to establish...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2000 |
| País: | Argentina |
| Institución: | Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales |
| Repositorio: | Biblioteca Digital (UBA-FCEN) |
| Idioma: | inglés |
| OAI Identifier: | paperaa:paper_14203049_v5_n3_p602_BellozasReinhard |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_14203049_v5_n3_p602_BellozasReinhard |
| Access Level: | acceso abierto |
| Palabra clave: | acetylcholinesterase insecticide organophosphorus compound sulfoximine unclassified drug computer simulation conference paper infrared radiation insecticidal activity measurement nuclear magnetic resonance phosphorylation structure analysis toxicity |
| Sumario: | New organophosphorus insecticides of dialkylsulphoximines derived with activity upon acetylcholinesterase were synthesized. The obtained compounds were characterized by NMR and IR, and anticholinesterase activity and toxicity was measured. A simulation through computer was done in order to establish the relationship between structure and activity. |
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