Relationship between physical and genetic distances along the zebra finch Z chromosome
Nine bacterial artificial chromosomes containing genes linked to the Z chromosome of the zebra finch (Taeniopygia guttata) were localized using FISH on synaptonemal complex spreads. Their positions were correlated with those previously reported on the mitotic Z chromosome, showing a linear relations...
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2008 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/151031 |
| Acceso en línea: | http://hdl.handle.net/11336/151031 |
| Access Level: | acceso abierto |
| Palabra clave: | MEIOSIS AVES SEX CHROMOSOMES https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| Sumario: | Nine bacterial artificial chromosomes containing genes linked to the Z chromosome of the zebra finch (Taeniopygia guttata) were localized using FISH on synaptonemal complex spreads. Their positions were correlated with those previously reported on the mitotic Z chromosome, showing a linear relationship between positions along the mitotic chromosome and its synaptonemal complex. Distances in cM between the genes were calculated using a cytological map of the crossing-over based on the distribution of MLH1 foci along the ZZ synaptonemal complex (MLH1-cM map). It is shown that physical and genetic distances lack a linear relationship along most of the chromosome length, due to clustering of crossover events around the telomeres. This relationship departs strongly from that observed in the chicken Z chromosome and reflects the existence of different recombination rates and patterns among birds in spite of wide genomic conservation. |
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