Pinning-depinning transition in a stochastic growth model for the evolution of cell colony fronts in a disordered medium
We study a stochastic lattice model for cell colony growth, which takes into account proliferation, diffusion, and rotation of cells, in a culture medium with quenched disorder. The medium is composed both by sites that inhibit any possible change in the internal state of the cells, representing the...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/47944 |
| Acceso en línea: | http://hdl.handle.net/11336/47944 |
| Access Level: | acceso abierto |
| Palabra clave: | Computer simulation of cell processes Interface structure and roughness Computational techniques; simulations Growth model universality class https://purl.org/becyt/ford/1.3 https://purl.org/becyt/ford/1 |
| Sumario: | We study a stochastic lattice model for cell colony growth, which takes into account proliferation, diffusion, and rotation of cells, in a culture medium with quenched disorder. The medium is composed both by sites that inhibit any possible change in the internal state of the cells, representing the disorder, as well as by active medium sites, that do not interfere with the cell dynamics. By means of Monte Carlo simulations we find that the velocity of the growing interface, which is taken as the order parameter of the model, strongly depends on the density of active medium sites ($ho_A$). In fact, the model presents a (continuous) second-order pinning-depinning transition at a certain critical value of $ho_A^{crit}$, such as for $ho_A>ho_A^{crit}$ the interface moves freely across the disordered medium, but for $ho_A<ho_a^{crit}$ the="" interface="" becomes="" irreversible="" pinned="" by="" disorder.="" determining="" relevant="" critical="" exponents,="" our="" study="" reveals="" that="" within="" depinned="" phase="" can="" be="" rationalized="" in="" terms="" of="" kardar-parisi-zhang="" universality="" class,="" but="" when="" approaching="" threshold,="" non-linear="" term="" equation="" tends="" to="" vanish="" and="" then="" belongs="" quenched="" edwards-wilkinson="" class.="" <="" body="" /> |
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