Sex Differences in insulin resistance in GABAB1 knock out mice

We have previously demonstrated that the absence of functional GABA B receptors (GABABRs) disturbs glucose homeostasis in GABAB1KO mice. The aim of this work was to extend our studies of these alterations in GABAB1KO mice and investigate the sexual differences therein.

Detalles Bibliográficos
Autores: Bonaventura, Maria Marta, Rodriguez, D., Ferreira, M. L., Crivello, Martin, Repetto, E. M., Bettler, B., Libertun, Carlos, Lux, Victoria Adela R.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/9728
Acceso en línea:http://hdl.handle.net/11336/9728
Access Level:acceso abierto
Palabra clave:DIABETES
INSULIN SIGNALIG
GABAB RECEPTORS
AKT ACTIVATION
NPY EXPRESSION
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:We have previously demonstrated that the absence of functional GABA B receptors (GABABRs) disturbs glucose homeostasis in GABAB1KO mice. The aim of this work was to extend our studies of these alterations in GABAB1KO mice and investigate the sexual differences therein.