Histopathological Lesions on central nervous system intoxication of goats by Ipomoea carnea spp fistulosa (Convolvulácea)

Ipomoea carnea var. fistulosa (Convolvulaceae) is a perenne poisonous plant, found throughout the Argentine Northeastern. The intoxication produces a lysosomal storage disease in goats, sheep and cattle. Five goats were fed with 50 g/kgBW/day of fresh leaves, flowers and stems of I. carnea, during 4...

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Detalles Bibliográficos
Autores: Ríos, E., Cholich, Luciana Andrea, Silva, J., Acosta de Pérez, O.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/60151
Acceso en línea:http://hdl.handle.net/11336/60151
Access Level:acceso abierto
Palabra clave:GOAT
INTOXICATION
IPOMOEA CARNEA
NERVOUS SYSTEM LESIONS
cabra
intoxicación
lesiones sistema nervioso
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
Descripción
Sumario:Ipomoea carnea var. fistulosa (Convolvulaceae) is a perenne poisonous plant, found throughout the Argentine Northeastern. The intoxication produces a lysosomal storage disease in goats, sheep and cattle. Five goats were fed with 50 g/kgBW/day of fresh leaves, flowers and stems of I. carnea, during 43–60 days. Hirsute coat, depression, difficulty to stand up, ataxia, hypermetria, wide–based stance, incoordination of muscular movements, intense tremors, spastic paresis, abnormal postural reactions, nystagmus, hyperreflexia, hypersensitivity to sound, head tilting and loss of equilibrium were observed in all treated animals. The histopathologic study revealed the presence of cytoplasmatic vacuolation mainly in medulla oblongata and cerebellum. Control animals did not show any alterations. We conclude that this poisoning causes central nervous system damage, being Purkinje cells the most severely affected