Restricted Outbreak of American Tegumentary Leishmaniasis with high microfocal transmission

Cutaneous leishmaniasis is endemic in Salta, the northwestern province of Argentina. We describe an outbreak involving five recreational hunters whose exposure was limited to several hours in a residual patch of primary forest. All patients presented with typical cutaneous lesions after a mean incub...

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Detalhes bibliográficos
Autores: Krolewiecki, Alejandro Javier, Gil, José Fernando, Quipildor, Marcelo, Cajal, Silvana P., Pravia, Carlos Alberto, Juarez, Marisa, Villalpando, Carlos, Locatelli, Fabricio M., Chanampa, Mariana del Milagro, Castillo, Gabriela, Oreste, Maria Fernanda, Hoyos, Carlos Lorenzo, Negri, Vanesa, Nasser, Julio Rubén
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/3075
Acesso em linha:http://hdl.handle.net/11336/3075
Access Level:acceso abierto
Palavra-chave:Leishmaniasis
Leishmania (V) Braziliensis
Lutozomyia Neivai
Outbreak
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Descrição
Resumo:Cutaneous leishmaniasis is endemic in Salta, the northwestern province of Argentina. We describe an outbreak involving five recreational hunters whose exposure was limited to several hours in a residual patch of primary forest. All patients presented with typical cutaneous lesions after a mean incubation period of 59 days (range 15–78), and one developed simultaneous mucosal involvement. Polymerase chain reaction analysis of lesions confirmed Leishmania (V.) braziliensis as the etiologic agent in three cases. All patients were cured with anti-Leishmania treatment. Entomologic surveys in the transmission area revealed a predominance of Lutzomyia neivai. This outbreak report confirms a microfocal transmission pattern of tegumentary leishmaniasis in the Americas and based on a well-determined exposure, allows the determination of incubation times for leishmaniasis caused by Leishmania braziliensis.