Memetic micro-genetic algorithms for cancer data classification

Fast and precise medical diagnosis of human cancer is crucial for treatment decisions. Gene selection consists of identifying a set of informative genes from microarray data to allow high predictive accuracy in human cancer classification. This task is a combinatorial search problem, and optimisatio...

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Detalles Bibliográficos
Autores: Rojas, Matias Gabriel, Olivera, Ana Carolina, Carballido, Jessica Andrea, Vidal, Pablo Javier
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/224126
Acceso en línea:http://hdl.handle.net/11336/224126
Access Level:acceso abierto
Palabra clave:CANCER MICROARRAY DATA
FEATURE SELECTION
MEMETIC ALGORITHMS
MICRO-GENETIC ALGORITHM
https://purl.org/becyt/ford/1.2
https://purl.org/becyt/ford/1
Descripción
Sumario:Fast and precise medical diagnosis of human cancer is crucial for treatment decisions. Gene selection consists of identifying a set of informative genes from microarray data to allow high predictive accuracy in human cancer classification. This task is a combinatorial search problem, and optimisation methods can be applied for its resolution. In this paper, two memetic micro-genetic algorithms (MμV1 and MμV2) with different hybridisation approaches are proposed for feature selection of cancer microarray data. Seven gene expression datasets are used for experimentation. The comparison with stochastic state-of-the-art optimisation techniques concludes that problem-dependent local search methods combined with micro-genetic algorithms improve feature selection of cancer microarray data.