Use of a Melanin-Type Polymer to Improve the Selectivity of Glucose Biosensors

This paper reports the advantages of using a melanin-type polymer to improve the selectivity of glucose biosensors based on carbon paste electrodes containing Pt and glucose oxidase (GOx). The resulting bioelectrodes combine the high sensitivity of metallized electrodes with the selectivity given by...

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Detalles Bibliográficos
Autores: Rubianes, María Dolores, Rivas, Gustavo Adolfo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/42651
Acceso en línea:http://hdl.handle.net/11336/42651
Access Level:acceso abierto
Palabra clave:Glucose Biosensor
Glucose Oxidase
Metallized Electrode
Melanic Polymer
Carbon Paste
Platinum
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:This paper reports the advantages of using a melanin-type polymer to improve the selectivity of glucose biosensors based on carbon paste electrodes containing Pt and glucose oxidase (GOx). The resulting bioelectrodes combine the high sensitivity of metallized electrodes with the selectivity given by the polymeric layer. They exhibit excellentperformance for glucose with a rapid response (around 10 sec per sample), a wide linear range (up to 3.0 10 2 M), low detection limits (60 mM) and a highly reproducible response (R.S.D. of 4.9%). The bioelectrodes are stable with prolonged use and almost free from the interference of easily oxidizable compounds found inbiological fluids, such as ascorbic acid (AA), uric acid (UA) and acetaminophen.