High-Resolution hyperpolarized J -spectra with parahydrogen discrimination
Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex system...
| Autores: | , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2013 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/185726 |
| Acceso en línea: | http://hdl.handle.net/11336/185726 |
| Access Level: | acceso abierto |
| Palabra clave: | CPMG HYPERPOLARIZATION NMR SPECTROSCOPY PARAHYDROGEN PASADENA PHIP PULSE SEQUENCE SPIN ECHOES https://purl.org/becyt/ford/1.3 https://purl.org/becyt/ford/1 |
| Sumario: | Parahydrogen-induced polarization (PHIP) has become a powerful tool not only to overcome the low intrinsic sensitivity of nuclear magnetic resonance (NMR) but also as a probe for catalytic reactions, as a contrast agent in magnetic resonance imaging (MRI), or in analytic chemistry. In complex systems, the antiphase signals coming from parahydrogen in a PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment) experiment can be partially canceled by the presence of large thermally polarized signals. In the present work, we present a simple method to separate the thermal and hyperpolrized contributions by taking advantage of their very different evolution during a modified CPMG sequence. The separation is obtained in combination with a property of the fast Fourier transform algorithm (FFT). The technique is experimentally demonstrated for a mixture of hyperpolarized 1-hexene and a large amount of CH2Cl2. |
|---|