Room-Temperature Photoinduced Direct C-H-Arylation via Base-Promoted Homolytic Aromatic Substitution

Conceptually different approach toward biaryl syntheses by photoinduced direct CH arylation of benzene and thiophene in the presence of t-BuOK is reported. The reaction proceeds through photo- and base-promoted homolytic aromatic substitution. The o-, m- and p- substituted ArI, as well as the electr...

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Detalles Bibliográficos
Autores: Buden, Maria Eugenia, Guastavino, Javier Fernando, Rossi, Roberto Arturo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/8791
Acceso en línea:http://hdl.handle.net/11336/8791
Access Level:acceso abierto
Palabra clave:Biaryls
C-H Arylation
Has
Photochemistry
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:Conceptually different approach toward biaryl syntheses by photoinduced direct CH arylation of benzene and thiophene in the presence of t-BuOK is reported. The reaction proceeds through photo- and base-promoted homolytic aromatic substitution. The o-, m- and p- substituted ArI, as well as the electron-donating and electron-withdrawing nature of the substituents were found be good to excellent substrates. Heteroaryl, ArBr, ArCl and double CH arylation were successfully achieved.