Bis(pyridine)iodonium Tetrafluoroborate (IPy2BF4): a versatile oxidizing reagent

The use of bis(pyridine)iodonium tetrafluoroborate (IPy2BF4) as an oxidizing agent towards different types of alcohols is reported. The observed reactivity involves different reaction pathways, as a function both of the structures of the starting materials and of the experimental conditions. Interes...

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Detalhes bibliográficos
Autores: Barluenga, José, González Bobes, Francisco, Murguia, Marcelo Cesar, Ananthoju, Sreenivasa, González, José
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/26833
Acesso em linha:http://hdl.handle.net/11336/26833
Access Level:acceso abierto
Palavra-chave:Oxidations
Iodations
Iodonium
Bis Pyridine Iodonium
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descrição
Resumo:The use of bis(pyridine)iodonium tetrafluoroborate (IPy2BF4) as an oxidizing agent towards different types of alcohols is reported. The observed reactivity involves different reaction pathways, as a function both of the structures of the starting materials and of the experimental conditions. Interestingly, the title iodine-containing compound is capable of a tuneable reaction with simple cycloalkanols, providing straight and selective access either to ω-iodocarbonyl compounds or to ketones, a previously unreported and chemoselective range of oxidation potential. Furthermore, appropriate conditions for the preparation of aldehydes and esters from primary alcohols by easily performed experimental procedures were also established. The β-scission reactions of cycloalkanols and the α-oxidation processes of primary, secondary and benzylic alcohols are discussed.