Toxic Effects of Patulin on Sheep

The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on day...

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Autores: Tapia, Maria Ofelia, Giordano, Antonio Felix Marcelo, Soraci, Alejandro Luis, González, Carlos A., Denzoin, Laura Andrea, Ortega, Irma, Olson, William, Murphy, Michael J.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/106499
Acceso en línea:http://hdl.handle.net/11336/106499
Access Level:acceso abierto
Palabra clave:PATULIN
SHEEP
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
id AR_c4250eddf89e97ffccff7a70396459cb
oai_identifier_str oai:ri.conicet.gov.ar:11336/106499
network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv Toxic Effects of Patulin on Sheep
title Toxic Effects of Patulin on Sheep
spellingShingle Toxic Effects of Patulin on Sheep
Tapia, Maria Ofelia
PATULIN
SHEEP
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
title_short Toxic Effects of Patulin on Sheep
title_full Toxic Effects of Patulin on Sheep
title_fullStr Toxic Effects of Patulin on Sheep
title_full_unstemmed Toxic Effects of Patulin on Sheep
title_sort Toxic Effects of Patulin on Sheep
dc.creator.none.fl_str_mv Tapia, Maria Ofelia
Giordano, Antonio Felix Marcelo
Soraci, Alejandro Luis
González, Carlos A.
Denzoin, Laura Andrea
Ortega, Irma
Olson, William
Murphy, Michael J.
author Tapia, Maria Ofelia
author_facet Tapia, Maria Ofelia
Giordano, Antonio Felix Marcelo
Soraci, Alejandro Luis
González, Carlos A.
Denzoin, Laura Andrea
Ortega, Irma
Olson, William
Murphy, Michael J.
author_role author
author2 Giordano, Antonio Felix Marcelo
Soraci, Alejandro Luis
González, Carlos A.
Denzoin, Laura Andrea
Ortega, Irma
Olson, William
Murphy, Michael J.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv PATULIN
SHEEP
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
topic PATULIN
SHEEP
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
description The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior.
publishDate 2006
dc.date.none.fl_str_mv 2006-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/106499
Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-276
1680-5593
1993-601X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/106499
identifier_str_mv Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-276
1680-5593
1993-601X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://medwelljournals.com/abstract/?doi=javaa.2006.271.276
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Medwell Online
publisher.none.fl_str_mv Medwell Online
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799194830725709824
spelling Toxic Effects of Patulin on SheepTapia, Maria OfeliaGiordano, Antonio Felix MarceloSoraci, Alejandro LuisGonzález, Carlos A.Denzoin, Laura AndreaOrtega, IrmaOlson, WilliamMurphy, Michael J.PATULINSHEEPhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior.Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Giordano, Antonio Felix Marcelo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: González, Carlos A.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Denzoin, Laura Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Ortega, Irma. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Olson, William. University of Minnesota; Estados UnidosFil: Murphy, Michael J.. University of Minnesota; Estados UnidosMedwell Online2006-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/106499Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-2761680-55931993-601XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://medwelljournals.com/abstract/?doi=javaa.2006.271.276info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:37:23Zoai:ri.conicet.gov.ar:11336/106499instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:37:24.26CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
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