Highly efficient palladium-catalyzed arsination. Synthesis of a biphenyl arsine ligand and its application to obtain perfluoroalkylarsines
An efficient one-pot, two-step Pd-catalyzed arsination with n-Bu 3SnAsPh2 (1) and sterically hindered aryl iodides (ArI) with different functional groups is reported. The cross-coupling reactions of this stannane with ArI afforded the functionalized triarylarsines in very good isolated yields (71-88...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2009 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/114039 |
| Acceso en línea: | http://hdl.handle.net/11336/114039 |
| Access Level: | acceso abierto |
| Palabra clave: | Arsination Arsine Ligands Palladium Organoheteroatom Stannanes https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Sumario: | An efficient one-pot, two-step Pd-catalyzed arsination with n-Bu 3SnAsPh2 (1) and sterically hindered aryl iodides (ArI) with different functional groups is reported. The cross-coupling reactions of this stannane with ArI afforded the functionalized triarylarsines in very good isolated yields (71-88%). By using this methodology, a biphenyl arsine ligand, AsPh2(bph), was achieved and its use as ligand in the Pd-catalyzed arsination with RfI to obtain perfluoroalkylarsines is also reported. In this reaction, the activity of a variety of phosphine and arsine ligands was investigated. The new biphenyl arsine ligand AsPh2(bph) proved to be the best one for the arsination reaction with RfI. |
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