The Role of Androgen Signaling in Male Sexual Development at Puberty

Puberty is characterized by major changes in the anatomy and function of reproductive organs. Androgen activity is low before puberty, but during pubertal development, the testes resume the production of androgens. Major physiological changes occur in the testicular cell compartments in response to...

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Detalles Bibliográficos
Autor: Rey, Rodolfo Alberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/158743
Acceso en línea:http://hdl.handle.net/11336/158743
Access Level:acceso abierto
Palabra clave:AMH
ANDROGEN RECEPTOR
LEYDIG
SERTOLI
TESTIS
TRANSCRIPTIONAL REGULATION
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
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spelling The Role of Androgen Signaling in Male Sexual Development at PubertyRey, Rodolfo AlbertoAMHANDROGEN RECEPTORLEYDIGSERTOLITESTISTRANSCRIPTIONAL REGULATIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Puberty is characterized by major changes in the anatomy and function of reproductive organs. Androgen activity is low before puberty, but during pubertal development, the testes resume the production of androgens. Major physiological changes occur in the testicular cell compartments in response to the increase in intratesticular testosterone concentrations and androgen receptor expression. Androgen activity also impacts on the internal and external genitalia. In target cells, androgens signal through a classical and a nonclassical pathway. This review addresses the most recent advances in the knowledge of the role of androgen signaling in postnatal male sexual development, with a special emphasis on human puberty.Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; ArgentinaOxford University Press2021-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/158743Rey, Rodolfo Alberto; The Role of Androgen Signaling in Male Sexual Development at Puberty; Oxford University Press; Endocrinology; 162; 2; 2-2021; 1-161945-7170CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1210/endocr/bqaa215info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/endo/article/162/2/bqaa215/5992296info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:34:30Zoai:ri.conicet.gov.ar:11336/158743instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:34:30.607CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The Role of Androgen Signaling in Male Sexual Development at Puberty
title The Role of Androgen Signaling in Male Sexual Development at Puberty
spellingShingle The Role of Androgen Signaling in Male Sexual Development at Puberty
Rey, Rodolfo Alberto
AMH
ANDROGEN RECEPTOR
LEYDIG
SERTOLI
TESTIS
TRANSCRIPTIONAL REGULATION
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
title_short The Role of Androgen Signaling in Male Sexual Development at Puberty
title_full The Role of Androgen Signaling in Male Sexual Development at Puberty
title_fullStr The Role of Androgen Signaling in Male Sexual Development at Puberty
title_full_unstemmed The Role of Androgen Signaling in Male Sexual Development at Puberty
title_sort The Role of Androgen Signaling in Male Sexual Development at Puberty
dc.creator.none.fl_str_mv Rey, Rodolfo Alberto
author Rey, Rodolfo Alberto
author_facet Rey, Rodolfo Alberto
author_role author
dc.subject.none.fl_str_mv AMH
ANDROGEN RECEPTOR
LEYDIG
SERTOLI
TESTIS
TRANSCRIPTIONAL REGULATION
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
topic AMH
ANDROGEN RECEPTOR
LEYDIG
SERTOLI
TESTIS
TRANSCRIPTIONAL REGULATION
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
description Puberty is characterized by major changes in the anatomy and function of reproductive organs. Androgen activity is low before puberty, but during pubertal development, the testes resume the production of androgens. Major physiological changes occur in the testicular cell compartments in response to the increase in intratesticular testosterone concentrations and androgen receptor expression. Androgen activity also impacts on the internal and external genitalia. In target cells, androgens signal through a classical and a nonclassical pathway. This review addresses the most recent advances in the knowledge of the role of androgen signaling in postnatal male sexual development, with a special emphasis on human puberty.
publishDate 2021
dc.date.none.fl_str_mv 2021-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/158743
Rey, Rodolfo Alberto; The Role of Androgen Signaling in Male Sexual Development at Puberty; Oxford University Press; Endocrinology; 162; 2; 2-2021; 1-16
1945-7170
CONICET Digital
CONICET
url http://hdl.handle.net/11336/158743
identifier_str_mv Rey, Rodolfo Alberto; The Role of Androgen Signaling in Male Sexual Development at Puberty; Oxford University Press; Endocrinology; 162; 2; 2-2021; 1-16
1945-7170
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1210/endocr/bqaa215
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/endo/article/162/2/bqaa215/5992296
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.811543

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