Omicron Breakthrough Infection after Heterologous Prime-Boost Vaccination Induces a Vigorous Antibody Response

Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is usually asymptomatic or mild and appears to be poorly immunogenic at least in unvaccinated individuals. Here, we found that health care workers vaccinated with 2 doses of Sputnik V and a booster dose o...

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Detalles Bibliográficos
Autores: Varese, Augusto, Mazzitelli, Bianca, Erra Diaz, Fernando Alberto, Kjolhede, María Victoria, Ojeda, Diego Sebastian, Vellicce, Alejandra Fabiana, Arto, Penélope, Cicero, Carla, Pascowsky, María, Figueras, Laura Victoria, Broese, Bárbara, Dávila, Rosa, Zarlenga, Rocío, Rivelli, Federico Martin, Verruno, Camila, Silenzi, Valeria, Beltran, Ivana Romina, Gamarnik, Andrea Vanesa, Ceballos, Ana, Zala, Carlos, Badolati, Adelina, Geffner, Jorge Raúl
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/212995
Acceso en línea:http://hdl.handle.net/11336/212995
Access Level:acceso abierto
Palabra clave:COVID-19
NEUTRALIZING ANTIBODIES
OMICRON
SARS-COV-2
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is usually asymptomatic or mild and appears to be poorly immunogenic at least in unvaccinated individuals. Here, we found that health care workers vaccinated with 2 doses of Sputnik V and a booster dose of ChAdOx1 mount a vigorous neutralizing-Antibody response after Omicron breakthrough infection.