Pareto front for chemotherapy scheludes

In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the...

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Detalhes bibliográficos
Autores: Barrea, Andres Alberto, Hernandez, Matias Ezequiel
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/210200
Acesso em linha:http://hdl.handle.net/11336/210200
Access Level:acceso abierto
Palavra-chave:Chemotherapy
Optimization multiobjetive
Mathematical Modeling
Cancer
https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
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spelling Pareto front for chemotherapy scheludesBarrea, Andres AlbertoHernandez, Matias EzequielChemotherapyOptimization multiobjetiveMathematical ModelingCancerhttps://purl.org/becyt/ford/1.1https://purl.org/becyt/ford/1In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer).Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; ArgentinaFil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; ArgentinaHikari2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/210200Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-58001312-885XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.m-hikari.com/ams/ams-2012/ams-113-116-2012/index.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:44:45Zoai:ri.conicet.gov.ar:11336/210200instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:44:45.938CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Pareto front for chemotherapy scheludes
title Pareto front for chemotherapy scheludes
spellingShingle Pareto front for chemotherapy scheludes
Barrea, Andres Alberto
Chemotherapy
Optimization multiobjetive
Mathematical Modeling
Cancer
https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
title_short Pareto front for chemotherapy scheludes
title_full Pareto front for chemotherapy scheludes
title_fullStr Pareto front for chemotherapy scheludes
title_full_unstemmed Pareto front for chemotherapy scheludes
title_sort Pareto front for chemotherapy scheludes
dc.creator.none.fl_str_mv Barrea, Andres Alberto
Hernandez, Matias Ezequiel
author Barrea, Andres Alberto
author_facet Barrea, Andres Alberto
Hernandez, Matias Ezequiel
author_role author
author2 Hernandez, Matias Ezequiel
author2_role author
dc.subject.none.fl_str_mv Chemotherapy
Optimization multiobjetive
Mathematical Modeling
Cancer
https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
topic Chemotherapy
Optimization multiobjetive
Mathematical Modeling
Cancer
https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
description In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer).
publishDate 2012
dc.date.none.fl_str_mv 2012-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/210200
Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-5800
1312-885X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/210200
identifier_str_mv Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-5800
1312-885X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.m-hikari.com/ams/ams-2012/ams-113-116-2012/index.html
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hikari
publisher.none.fl_str_mv Hikari
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.811543

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