Coxiella burnetii: Living inside the host cell
Coxiella burnetii is an obligate intracellular pathogen, causal agent of Q fever. In this brief review, we describe how recent described mechanisms help our understanding of C. burnetii invasion and his survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuol...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2018 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/94121 |
| Acceso en línea: | http://hdl.handle.net/11336/94121 |
| Access Level: | acceso abierto |
| Palabra clave: | ACTIN COXIELLOSIS PHAGOCYTIC PATHWAY Q FEVER https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| Sumario: | Coxiella burnetii is an obligate intracellular pathogen, causal agent of Q fever. In this brief review, we describe how recent described mechanisms help our understanding of C. burnetii invasion and his survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of C. burnetii, and we discuss the contribution of diverse degradative pathway of the cell during the formation and stabilization of the Coxiella-containing vacuole. |
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