QSPR Studies on Refractive Indices of Structurally Heterogeneous Polymers

We developed a predictive Quantitative Structure–Property Relationship (QSPR) for the refractive indices of 234 structurally diverse polymers. The model involves a single molecular descriptor and a conformation-independent approach. The most appropriate polymer structure representation was investiga...

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Detalles Bibliográficos
Autores: Duchowicz, Pablo Román, Fioressi, Silvina Ethel, Bacelo, Daniel Enrique, Saavedra Reyes, Laura Marcela, Toropova, Alla P., Toropov, Andrey A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/5477
Acceso en línea:http://hdl.handle.net/11336/5477
Access Level:acceso abierto
Palabra clave:Qspr Theory
Polymer
Refractive Index
Graph Theory
Coral Software
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:We developed a predictive Quantitative Structure–Property Relationship (QSPR) for the refractive indices of 234 structurally diverse polymers. The model involves a single molecular descriptor and a conformation-independent approach. The most appropriate polymer structure representation was investigated by considering 1–5 monomeric repeating units. The established equations were validated and tested through various well-known techniques, such as the use of an external test set of compounds, the Cross-Validation method, Y-Randomization and Applicability Domain, and finally a comparison was also performed to published results from the li terature. The developed QSPR could be useful for assisting the development of new polymeric materials.