Synthesis and Characterization of Gold@Gold(I)-Thiomalate Core@Shell Nanoparticles

In this paper, the synthesis of gold@gold(I)−thiolate core@shell nanoparticles is described for the first time. The chemical nature and structure of these nanoparticles were characterized by a multi-technique approach. The prepared particles consist of gold metallic cores, about 1 nm in size, surrou...

Descripción completa

Detalles Bibliográficos
Autores: Corthey, Gastón, Giovanetti, Lisandro José, Ramallo López, José Martín, Zelaya, Eugenia, Rubert, Aldo Alberto, Benitez, Guillermo Alfredo, Requejo, Félix Gregorio, Fonticelli, Mariano Hernán, Salvarezza, Roberto Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Institución:Universidad Nacional de La Plata
Repositorio:SEDICI (UNLP)
Idioma:inglés
OAI Identifier:oai:sedici.unlp.edu.ar:10915/159835
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/159835
Access Level:acceso abierto
Palabra clave:Ciencias Exactas
Química
gold nanoparticles
core@shell nanoparticles
thiomalic acid
mercaptosuccinic acid
gold(I)-thiomalate
rheumatoid arthritis
antiarthritic drugs
Descripción
Sumario:In this paper, the synthesis of gold@gold(I)−thiolate core@shell nanoparticles is described for the first time. The chemical nature and structure of these nanoparticles were characterized by a multi-technique approach. The prepared particles consist of gold metallic cores, about 1 nm in size, surrounded by stable gold(I)−thiomalate shells (Au@Au(I)−TM). These nanoparticles could be useful in medicine due to the interesting properties that gold(I)−thiomalate has against rheumatoid arthritis. Furthermore, the described results give new insights in the synthesis and characterization of metallic and core@shell nanoparticles.